Hypercalcemia

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Words List(answer : question or clue)

Fourteen : Cutoff value considered to be indicative of severe hypercalcemia
Nausea : Side effect associated with calcitonin
RANKL : Denosumab is a monoclonal antibody which binds to what cytokine?
Osteonecrosis : Repetitive IV use of bisphosphonates has been associated with risk of developing this rare complication
Prednisone :  Treatment for hypercalcemia in patients with chronic granulomatous diseases like sarcoidosis and lymphoma
Calcium : A mineral necessary to build and maintain strong bones and teeth, which also aids a number of other body processes
Denosumab : Treatment option for hypercalcemia in patients with renal disease (administer with calcitonin)
Osteoclast : A large multinucleated bone cell which absorbs bone tissue during growth and healing.
Dialysis : Last resort treatment for refractory hypercalcemia
Saline : Type of fluid to start first in treatment of hypercalcemia
Calcitonin : Reduces the serum calcium concentration by increasing renal calcium excretion and by decreasing bone resorption via interference with osteoclast function
Bisphosphonates : Nonhydrolyzable analogs of inorganic pyrophosphate inhibit calcium release by interfering with osteoclast-mediated bone resorption

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